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KMID : 1225720130050040242
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Allergy, Asthma & Immunology Research : AAIR
2013 Volume.5 No. 4 p.242 ~ p.244
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Acute Eosinophilic Pneumonia Leading to Acute Respiratory Failure in a Current Systemic Corticosteroid User
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Shin Hwa-Yong
Choe Ju-Won
Kwon Min-Suk
Jang Ju-Young
Jung Jae-Woo
Choi Jae-Chol
Shin Jong-Wook
Park In-Won
Choi Byoung-Whui
Kim Jae-Yeol
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Abstract
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A 69-year-old female patient visited the emergency room with fever (38.3℃) and dyspnea. She had been taking prednisolone (5 mg once per day) and methotrexate (2.5 mg once per week) for rheumatoid arthritis for 2 years. Chest computed tomography (CT) showed bilateral, multifocal ground glass opacity with interlobular septal thickening. Peripheral blood leukocyte count was 6,520/mm3 (neutrophils, 77.4%; eosinophils, 12.1%). During the night, mechanical ventilation was initiated due to the development of severe hypoxemia. Bronchoalveolar lavage fluid showed a high proportion of eosinophils (49%). Her symptoms improved dramatically after commencement of intravenous methylprednisolone therapy. This is the first report of idiopathic acute eosinophilic pneumonia developing in a current user of systemic corticosteroids.
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KEYWORD
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Acute eosinophilic pneumonia, respiratory failure, corticosteroid
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